{"id":313,"date":"2023-01-13T16:36:00","date_gmt":"2023-01-13T16:36:00","guid":{"rendered":"https:\/\/robustcircuit.flygen.org\/?p=313"},"modified":"2023-01-13T16:39:11","modified_gmt":"2023-01-13T16:39:11","slug":"new-research-paper-on-synapse-stabilization-by-suppression-of-membrane-degradation-project-p2","status":"publish","type":"post","link":"https:\/\/robustcircuit.flygen.org\/?p=313","title":{"rendered":"New research paper on synapse stabilization by suppression of membrane degradation (Project P2)"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0960982222019765\" target=\"_blank\" rel=\"noreferrer noopener\">EGFR-dependent suppression of synaptic autophagy<br>is required for neuronal circuit development<\/a><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Suchetana B. Dutta, Gerit Arne Linneweber, Maheva Andriatsilavo, Peter Robin Hiesinger*, Bassem A. Hassan*, <em>* co-corresponding authors<\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>In brief<\/strong><br>Using the development of the fruit fly Drosophila melanogaster brain as a model system, Dutta et al. identify a critical developmental period during which coupling axon branching to synaptic degradation is required for neural circuit formation. This coupling relies on EGFR-dependent restriction of local synaptic degradation.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>EGFR-dependent suppression of synaptic autophagyis required for neuronal circuit development Suchetana B. Dutta, Gerit Arne Linneweber, Maheva Andriatsilavo, Peter Robin Hiesinger*, Bassem A. Hassan*, * co-corresponding authors In briefUsing the&hellip;<\/p>\n","protected":false},"author":1,"featured_media":316,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-313","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-publications"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>New research paper on synapse stabilization by suppression of membrane degradation (Project P2) - RobustCircuit<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/robustcircuit.flygen.org\/?p=313\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"New research paper on synapse stabilization by suppression of membrane degradation (Project P2) - RobustCircuit\" \/>\n<meta property=\"og:description\" content=\"EGFR-dependent suppression of synaptic autophagyis required for neuronal circuit development Suchetana B. 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